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Role of PARP and TRPM2 in VEGF Inhibitor‐Induced Vascular Dysfunction

BACKGROUND: Hypertension and vascular toxicity are major unwanted side effects of antiangiogenic drugs, such as vascular endothelial growth factor inhibitors (VEGFis), which are effective anticancer drugs but have unwanted side effects, including vascular toxicity and hypertension. Poly (ADP‐ribose)...

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Detalles Bibliográficos
Autores principales: Neves, Karla B., Alves‐Lopes, Rheure, Montezano, Augusto C., Touyz, Rhian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111475/
https://www.ncbi.nlm.nih.gov/pubmed/36802924
http://dx.doi.org/10.1161/JAHA.122.027769