Diabetes Induces Cardiac Fibroblast Activation, Promoting a Matrix‐Preserving Nonmyofibroblast Phenotype, Without Stimulating Pericyte to Fibroblast Conversion

BACKGROUND: Interstitial and perivascular fibrosis may contribute to diabetes‐associated heart failure. Pericytes can convert to fibroblasts under conditions of stress and have been implicated in the pathogenesis of fibrotic diseases. We hypothesized that in diabetic hearts, pericytes may convert to...

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Detalles Bibliográficos
Autores principales: Alex, Linda, Tuleta, Izabela, Hanna, Anis, Frangogiannis, Nikolaos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111546/
https://www.ncbi.nlm.nih.gov/pubmed/36892073
http://dx.doi.org/10.1161/JAHA.122.027463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111546/
https://www.ncbi.nlm.nih.gov/pubmed/36892073
http://dx.doi.org/10.1161/JAHA.122.027463

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