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Roles of sex hormones in mediating the causal effect of vitamin D on osteoporosis: A two-step Mendelian randomization study

BACKGROUND: Although 25-hydroxyvitamin D [25(OH)D] is a risk factor for osteoporosis, it is not clear whether sex hormones mediate this casual association. We aimed to explore how sex hormones affect the association between 25(OH)D and osteoporosis to provide meaningful insights on the underlying me...

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Detalles Bibliográficos
Autores principales: Du, Yongwei, Xie, Baohui, Wang, Maoyuan, Zhong, Yanbiao, Lv, Zhimai, Luo, Yun, He, Qiwei, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111617/
https://www.ncbi.nlm.nih.gov/pubmed/37082118
http://dx.doi.org/10.3389/fendo.2023.1159241