Cargando…

Roles of sex hormones in mediating the causal effect of vitamin D on osteoporosis: A two-step Mendelian randomization study

BACKGROUND: Although 25-hydroxyvitamin D [25(OH)D] is a risk factor for osteoporosis, it is not clear whether sex hormones mediate this casual association. We aimed to explore how sex hormones affect the association between 25(OH)D and osteoporosis to provide meaningful insights on the underlying me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Du, Yongwei, Xie, Baohui, Wang, Maoyuan, Zhong, Yanbiao, Lv, Zhimai, Luo, Yun, He, Qiwei, Liu, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111617/ https://www.ncbi.nlm.nih.gov/pubmed/37082118 http://dx.doi.org/10.3389/fendo.2023.1159241

Ejemplares similares

Use of Mendelian Randomization to Examine Causal Inference in Osteoporosis
por: Zheng, Jie, et al.
Publicado: (2019)

The causal relationship between autoimmune diseases and osteoporosis: a study based on Mendelian randomization
por: Wu, Shaofeng, et al.
Publicado: (2023)

Causal relationship between osteoporosis and osteoarthritis: A two-sample Mendelian randomized study
por: Lin, Liu, et al.
Publicado: (2022)

Mendelian randomization analysis does not reveal a causal influence of mental diseases on osteoporosis
por: Tang, Fen, et al.
Publicado: (2023)

No genetic causal association between iron status and osteoporosis: A two-sample Mendelian randomization
por: Xu, Jiawen, et al.
Publicado: (2022)

Causal association of NAFLD with osteoporosis, fracture and falling risk: a bidirectional Mendelian randomization study
por: Cui, Aiyong, et al.
Publicado: (2023)

Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: an observational and Mendelian randomization study
por: Cai, Xinting, et al.
Publicado: (2023)

Causal relationships between sex hormone traits, lifestyle factors, and osteoporosis in men: A Mendelian randomization study
por: Wang, Hui, et al.
Publicado: (2022)

Inferring causal effects of homocysteine and B-vitamin concentrations on bone mineral density and fractures: Mendelian randomization analyses
por: Fu, Liwan, et al.
Publicado: (2022)

Mendelian randomization supports the causal role of fasting glucose on periodontitis
por: Wang, Yi, et al.
Publicado: (2022)

Causal relationships between rheumatism and dyslipidemia: A two-sample Mendelian randomization study
por: Zhang, Guangyang, et al.
Publicado: (2022)

Associations between genetically predicted sex and growth hormones and facial aging in the UK Biobank: a two−sample Mendelian randomization study
por: Zhao, Mingjian, et al.
Publicado: (2023)

Causal associations between thyroid dysfunction and COVID-19 susceptibility and severity: A bidirectional Mendelian randomization study
por: Zhang, Zhihao, et al.
Publicado: (2022)

Causal relationship between polycystic ovary syndrome and chronic kidney disease: A Mendelian randomization study
por: Du, Yufei, et al.
Publicado: (2023)

Investigating the causal mediating effect of type 2 diabetes on the relationship between traits and systolic blood pressure: A two-step Mendelian randomization study
por: Hao, Xuezeng, et al.
Publicado: (2022)

The causal effects of thyroid function and lipids on cholelithiasis: A Mendelian randomization analysis
por: Chen, Junhong, et al.
Publicado: (2023)

Causality between sarcopenia and diabetic nephropathy: a bidirectional Mendelian randomization study
por: Ren, Linan, et al.
Publicado: (2023)

Causal association between metabolic syndrome and cholelithiasis: a Mendelian randomization study
por: Zhu, Qi, et al.
Publicado: (2023)

Osteoporosis and sarcopenia-related traits: A bi-directional Mendelian randomization study
por: Liu, Chao, et al.
Publicado: (2022)

Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study
por: He, Lijuan, et al.
Publicado: (2022)

The causal effect of obesity on diabetic retinopathy: A two-sample Mendelian randomization study
por: Zheng, Changwei, et al.
Publicado: (2023)

Causal relationship between circulating lipid traits and periodontitis: univariable and multivariable Mendelian randomization
por: Hu, Gaofu, et al.
Publicado: (2023)

Sex Steroids and Osteoarthritis: A Mendelian Randomization Study
por: Yan, Yi-Shang, et al.
Publicado: (2021)

Causal Effect of Visceral Adipose Tissue Accumulation on the Human Longevity: A Mendelian Randomization Study
por: Yan, Bin, et al.
Publicado: (2021)

Causal Effect of Blood Pressure on Bone Mineral Density and Fracture: A Mendelian Randomization Study
por: He, Bin, et al.
Publicado: (2021)

Causal relationships of obesity on musculoskeletal chronic pain: A two-sample Mendelian randomization study
por: Chen, Xiaoqing, et al.
Publicado: (2022)

The causal association between bone mineral density and risk of osteoarthritis: A Mendelian randomization study
por: Jiang, Liying, et al.
Publicado: (2023)

Causal associations of hyperthyroidism with prostate cancer, colon cancer, and leukemia: a Mendelian randomization study
por: Xu, Feipeng, et al.
Publicado: (2023)

Mendelian randomization indicates a causal contribution of type 2 diabetes to retinal vein occlusion
por: Huang, Jian
Publicado: (2023)

Putative causal inference for the relationship between obesity and sex hormones in males: a bidirectional Mendelian randomization study
por: Wan, Bangbei, et al.
Publicado: (2023)

Causal Effects of Genetically Determined Metabolites on Risk of Polycystic Ovary Syndrome: A Mendelian Randomization Study
por: Sun, Shuliu, et al.
Publicado: (2020)

Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study
por: Yoshiji, Satoshi, et al.
Publicado: (2022)

Mendelian randomization study supports the causal association between serum cystatin C and risk of diabetic nephropathy
por: Feng, Baiyu, et al.
Publicado: (2022)

Causal relationship between thyroid dysfunction and hallux valgus: A two-sample Mendelian randomization study
por: Xiong, Binglang, et al.
Publicado: (2023)

Causality between urate levels with sarcopenia-related traits: a bi-directional Mendelian randomization study
por: Lin, Yanze, et al.
Publicado: (2023)

Causal effects of nonalcoholic fatty liver disease on cerebral cortical structure: a Mendelian randomization analysis
por: Mai, Zhiliang, et al.
Publicado: (2023)

Investigating causal associations among gut microbiota, metabolites, and liver diseases: a Mendelian randomization study
por: Zhang, Lilong, et al.
Publicado: (2023)

The role of vitamin D on rotator cuff tear with osteoporosis
por: Liu, Gejun, et al.
Publicado: (2022)

Osteoporosis and dermatoporosis: a review on the role of vitamin D
por: Romano, Fiammetta, et al.
Publicado: (2023)

Mendelian randomization study of thyroid function and anti-Müllerian hormone levels
por: Liang, Zhu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vlmg58nt56rv3bmr7106ieifpu