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Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2

BACKGROUND: Lactobacillus has been demonstrated to serve a protective role in intestinal injury. However, the relationship between Lactobacillus murinus (L. murinus)-derived tryptophan metabolites and intestinal ischemia/reperfusion (I/R) injury yet to be investigated. This study aimed to evaluate t...

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Detalles Bibliográficos
Autores principales: Zhang, Fang-Ling, Chen, Xiao-Wei, Wang, Yi-Fan, Hu, Zhen, Zhang, Wen-Juan, Zhou, Bo-Wei, Ci, Peng-Fei, Liu, Ke-Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111656/
https://www.ncbi.nlm.nih.gov/pubmed/37072757
http://dx.doi.org/10.1186/s12967-023-04109-3