Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

BACKGROUND: Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis. The low efficacy of current treatment options highlights the urge to identify more effective therapies aimed at improving MM patients’ survival. Bortezomib (Bor) is a specific and reversible inhibitor of the chymotrypsi...

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Detalles Bibliográficos
Autores principales: Benvenuto, Monica, Angiolini, Valentina, Focaccetti, Chiara, Nardozi, Daniela, Palumbo, Camilla, Carrano, Raffaele, Rufini, Alessandra, Bei, Riccardo, Miele, Martino Tony, Mancini, Patrizia, Barillari, Giovanni, Cirone, Mara, Ferretti, Elisabetta, Tundo, Grazia Raffaella, Mutti, Luciano, Masuelli, Laura, Bei, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111665/
https://www.ncbi.nlm.nih.gov/pubmed/37069690
http://dx.doi.org/10.1186/s13062-023-00374-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111665/
https://www.ncbi.nlm.nih.gov/pubmed/37069690
http://dx.doi.org/10.1186/s13062-023-00374-w

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