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Pathogenic sphingosine 1-phosphate pathway in psoriasis: a critical review of its pathogenic significance and potential as a therapeutic target

Sphingosine-1-phosphate (S1P) is a sphingolipid mediator that exerts a variety of biological functions, including immune, cardiovascular, and neurological regulation as well as tumor promotion, through high-affinity G protein-coupled receptors (S1P(1-5)). It has been reported that circulating S1P le...

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Detalles Bibliográficos
Autores principales: Zhao, Yuechun, Zhang, Yuheng, Li, Jiaqi, Zhang, Ningxin, Jin, Qiubai, Qi, Yuxia, Song, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111724/
https://www.ncbi.nlm.nih.gov/pubmed/37072847
http://dx.doi.org/10.1186/s12944-023-01813-3