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Artemisinin derivatives induce oxidative stress leading to DNA damage and caspase-mediated apoptosis in Theileria annulata-transformed cells

BACKGROUND: Bovine theileriosis caused by the eukaryotic parasite Theileria annulata is an economically important tick-borne disease. If it is not treated promptly, this lymphoproliferative disease has a significant fatality rate. Buparvaquone (BPQ) is the only chemotherapy-based treatment available...

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Detalles Bibliográficos
Autores principales: Barman, Madhumanti, Dandasena, Debabrata, Suresh, Akash, Bhandari, Vasundhra, Kamble, Sonam, Singh, Sakshi, Subudhi, Madhusmita, Sharma, Paresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111749/
https://www.ncbi.nlm.nih.gov/pubmed/37069625
http://dx.doi.org/10.1186/s12964-023-01067-7