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TM4SF1 upregulates MYH9 to activate the NOTCH pathway to promote cancer stemness and lenvatinib resistance in HCC

TM4SF1, a member of the transmembrane 4 superfamily, is crucial for both healthy and malignant human tissues. The significant function of TM4SF1 in the incidence and progression of cancer has been widely recognized in recent years. Although some achievements have been made in the study of TM4SF1, th...

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Detalles Bibliográficos
Autores principales: Yang, Si-bo, Zhou, Zi-han, Lei, Jin, Li, Xiao-wen, Chen, Qian, Li, Bo, Zhang, Ye-wei, Ge, Yu-zhen, Zuo, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111829/
https://www.ncbi.nlm.nih.gov/pubmed/37069693
http://dx.doi.org/10.1186/s13062-023-00376-8