Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation

Pioneer transcription factors are thought to play pivotal roles in developmental processes by binding nucleosomal DNA to activate gene expression, though mechanisms through which pioneer transcription factors remodel chromatin remain unclear. Here, using single-cell transcriptomics, we show that end...

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Detalles Bibliográficos
Autores principales: Păun, Oana, Tan, Yu Xuan, Patel, Harshil, Strohbuecker, Stephanie, Ghanate, Avinash, Cobolli-Gigli, Clementina, Llorian Sopena, Miriam, Gerontogianni, Lina, Goldstone, Robert, Ang, Siew-Lan, Guillemot, François, Dias, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111863/
https://www.ncbi.nlm.nih.gov/pubmed/36931659
http://dx.doi.org/10.1101/gad.350269.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111863/
https://www.ncbi.nlm.nih.gov/pubmed/36931659
http://dx.doi.org/10.1101/gad.350269.122

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