Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model

A regimen comprised of bedaquiline (BDQ, or B), pretomanid, and linezolid (BPaL) is the first oral 6-month regimen approved by the U.S. Food and Drug Administration and recommended by the World Health Organization for the treatment of extensively drug-resistant tuberculosis. We used a well-establish...

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Detalles Bibliográficos
Autores principales: Li, Si-Yang, Converse, Paul J., Betoudji, Fabrice, Lee, Jin, Mdluli, Khisimuzi, Upton, Anna, Fotouhi, Nader, Nuermberger, Eric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112056/
https://www.ncbi.nlm.nih.gov/pubmed/36920217
http://dx.doi.org/10.1128/aac.00035-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112056/
https://www.ncbi.nlm.nih.gov/pubmed/36920217
http://dx.doi.org/10.1128/aac.00035-23

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