Side-by-Side Profiling of Oxazolidinones to Estimate the Therapeutic Window against Mycobacterial Infections

New oxazolidinones are in clinical development for the treatment of tuberculosis and nontuberculous mycobacterial (NTM) infections, as a replacement for linezolid and tedizolid, which cause mitochondrial toxicity after prolonged treatment. Here, we carried out side-by-side measurements of mitochondr...

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Detalles Bibliográficos
Autores principales: Negatu, Dereje A., Aragaw, Wassihun Wedajo, Cangialosi, Julianna, Dartois, Véronique, Dick, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112060/
https://www.ncbi.nlm.nih.gov/pubmed/36920191
http://dx.doi.org/10.1128/aac.01655-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112060/
https://www.ncbi.nlm.nih.gov/pubmed/36920191
http://dx.doi.org/10.1128/aac.01655-22

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