Determining the Delamanid Pharmacokinetics/Pharmacodynamics Susceptibility Breakpoint Using Monte Carlo Experiments

Antimicrobial susceptibility testing, based on clinical breakpoints that incorporate pharmacokinetics/pharmacodynamics (PK/PD) and clinical outcomes, is becoming a new standard in guiding individual patient therapy as well as for drug resistance surveillance. However, for most antituberculosis drugs...

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Detalles Bibliográficos
Autores principales: Liu, Yongge, Moodley, Mischka, Pasipanodya, Jotam G., Gumbo, Tawanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Susceptibility
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112185/
https://www.ncbi.nlm.nih.gov/pubmed/36877034
http://dx.doi.org/10.1128/aac.01401-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112185/
https://www.ncbi.nlm.nih.gov/pubmed/36877034
http://dx.doi.org/10.1128/aac.01401-22

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