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The Natural Stilbenoid (–)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9

Despite effective combination antiretroviral therapy (cART), people living with HIV (PLWH) continue to harbor replication-competent and transcriptionally active virus in infected cells, which in turn can lead to ongoing viral antigen production, chronic inflammation, and increased risk of age-relate...

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Detalles Bibliográficos
Autores principales: Tietjen, Ian, Schonhofer, Cole, Sciorillo, Amanda, Naidu, Maya E., Haq, Zahra, Kannan, Toshitha, Kossenkov, Andrew V., Rivera-Ortiz, Jocelyn, Mounzer, Karam, Hart, Colin, Gyampoh, Kwasi, Yuan, Zhe, Beattie, Karren D., Rali, Topul, Shuda McGuire, Kristy, Davis, Rohan A., Montaner, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112218/
https://www.ncbi.nlm.nih.gov/pubmed/36975214
http://dx.doi.org/10.1128/aac.01600-22