High-throughput AR dimerization assay identifies androgen disrupting chemicals and metabolites

Introduction: Analysis of streamlined computational models used to predict androgen disrupting chemicals revealed that assays measuring androgen receptor (AR) cofactor recruitment/dimerization were particularly indispensable to high predictivity, especially for AR antagonists. As the original dimeri...

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Detalles Bibliográficos
Autores principales: Brown, Evan C., Hallinger, Daniel R., Simmons, Steven O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112521/
https://www.ncbi.nlm.nih.gov/pubmed/37082740
http://dx.doi.org/10.3389/ftox.2023.1134783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112521/
https://www.ncbi.nlm.nih.gov/pubmed/37082740
http://dx.doi.org/10.3389/ftox.2023.1134783

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