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High-throughput AR dimerization assay identifies androgen disrupting chemicals and metabolites

Introduction: Analysis of streamlined computational models used to predict androgen disrupting chemicals revealed that assays measuring androgen receptor (AR) cofactor recruitment/dimerization were particularly indispensable to high predictivity, especially for AR antagonists. As the original dimeri...

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Detalles Bibliográficos
Autores principales:	Brown, Evan C., Hallinger, Daniel R., Simmons, Steven O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112521/ https://www.ncbi.nlm.nih.gov/pubmed/37082740 http://dx.doi.org/10.3389/ftox.2023.1134783

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