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Transient Viral Rebound in Children with Perinatally Acquired HIV-1 Induces a Unique Soluble Immunometabolic Signature Associated with Decreased CD4/CD8 Ratio

BACKGROUND: To determine by multi-omic analysis changes in metabolites, lipids, and proteins as a consequence of transient viral rebound (tVR) in children with perinatally acquired HIV-1 (PHIV). METHODS: Plasma samples from children with PHIV and with tVR (first episode of transient RNA-HIV viral lo...

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Detalles Bibliográficos
Autores principales: Tarancon-Diez, Laura, Peraire, Joaquim, Jiménez de Ory, Santiago, Guirro, Maria, Escosa, Luis, Prieto Tato, Luis Manuel, Penín Antón, María, Piqueras, Ana Isabel, Vázquez Pérez, Álvaro, Gavilán, César, Bustillo-Alonso, Matilde, Navarro, María Luisa, Viladés, Consuelo, Vidal, Francesc, Rull, Anna, Muñoz-Fernández, María Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112677/
https://www.ncbi.nlm.nih.gov/pubmed/36727571
http://dx.doi.org/10.1093/jpids/piad008