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Porphyromonas gingivalis induction of TLR2 association with Vinculin enables PI3K activation and immune evasion

Porphyromonas gingivalis is a Gram-negative anaerobic bacterium that thrives in the inflamed environment of the gingival crevice, and is strongly associated with periodontal disease. The host response to P. gingivalis requires TLR2, however P. gingivalis benefits from TLR2-driven signaling via activ...

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Detalles Bibliográficos
Autores principales: Pandi, Karthikeyan, Angabo, Sarah, Gnanasekaran, Jeba, Makkawi, Hasnaa, Eli-Berchoer, Luba, Glaser, Fabian, Nussbaum, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112799/
https://www.ncbi.nlm.nih.gov/pubmed/37023213
http://dx.doi.org/10.1371/journal.ppat.1011284