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Knockout of the neonatal Fc receptor alters immune complex trafficking and lysosomal function in cultured podocytes

Podocytes are key to preventing the filtration of serum proteins into the urine. Recent evidence also suggests that in immune mediated kidney diseases, podocytes are the targets of immune complexes (ICs). The mechanisms whereby podocytes handle and respond to ICs remain unknown. The neonatal Fc rece...

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Detalles Bibliográficos
Autores principales: Haddad, George, Dylewski, James, Evans, River, Lewis, Linda, Blaine, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112810/
https://www.ncbi.nlm.nih.gov/pubmed/37071647
http://dx.doi.org/10.1371/journal.pone.0284636