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Complement Inhibition in Paroxysmal Nocturnal Hemoglobinuria (PNH): A Systematic Review and Expert Opinion from Central Europe on Special Patient Populations

INTRODUCTION: Hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) is complement-mediated due to the lack of complement inhibitors in the hemopoietic cell membranes, making complement inhibition the best approach to manage PNH. Three complement inhibitors are approved by the European Medicines Age...

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Detalles Bibliográficos
Autores principales: Bodó, Imre, Amine, Ismail, Boban, Ana, Bumbea, Horia, Kulagin, Alexander, Lukina, Elena, Piekarska, Agnieszka, Zupan, Irena Preloznik, Sokol, Juraj, Windyga, Jerzy, Cermak, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112829/
https://www.ncbi.nlm.nih.gov/pubmed/37072660
http://dx.doi.org/10.1007/s12325-023-02510-4