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Development and Validation of an Anion Exchange High-Performance Liquid Chromatography Method for Analysis of Empty Capsids and Capsids Encapsidating Genetic Material in a Purified Preparation of Recombinant Adeno-Associated Virus Serotype 5

The development of various manufacturing platforms and analytical technologies has substantially contributed to successfully translating the recombinant adeno-associated viral vector from the laboratory to the clinic. The active deployment of these analytical technologies for process and product cha...

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Detalles Bibliográficos
Autores principales: Joshi, Pranav R.H., Bernier, Alice, Chahal, Parminder S., Kamen, Amine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112873/
https://www.ncbi.nlm.nih.gov/pubmed/33860673
http://dx.doi.org/10.1089/hum.2020.317