Characterization of Adeno-Associated Virus Capsid Proteins with Two Types of VP3-Related Components by Capillary Gel Electrophoresis and Mass Spectrometry

Recombinant adeno-associated virus is a leading platform in human gene therapy. The adeno-associated virus (AAV) capsid is composed of three viral proteins (VPs): VP1, VP2, and VP3. To ensure the safety of AAV-based gene therapy products, the stoichiometry of VPs of AAV vector should be carefully mo...

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Detalles Bibliográficos
Autores principales: Oyama, Hiroaki, Ishii, Kentaro, Maruno, Takahiro, Torisu, Tetsuo, Uchiyama, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112878/
https://www.ncbi.nlm.nih.gov/pubmed/34082578
http://dx.doi.org/10.1089/hum.2021.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112878/
https://www.ncbi.nlm.nih.gov/pubmed/34082578
http://dx.doi.org/10.1089/hum.2021.009

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