A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans

Neuropeptides, including insulin, are important regulators of physiological functions of the organisms. Trafficking through the Golgi is crucial for the regulation of secretion of insulin-like peptides. ASNA-1 (TRC40) and ENPL-1 (GRP94) are conserved insulin secretion regulators in Caenorhabditis el...

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Detalles Bibliográficos
Autores principales: Podraza-Farhanieh, Agnieszka, Raj, Dorota, Kao, Gautam, Naredi, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112894/
https://www.ncbi.nlm.nih.gov/pubmed/36939052
http://dx.doi.org/10.1242/dev.201035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112894/
https://www.ncbi.nlm.nih.gov/pubmed/36939052
http://dx.doi.org/10.1242/dev.201035

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