Endothelial deletion of Wt1 disrupts coronary angiogenesis and myocardium development

Wt1 encodes a zinc finger protein that is crucial for epicardium development. Although WT1 is also expressed in coronary endothelial cells (ECs), the abnormal heart development observed in Wt1 knockout mice is mainly attributed to its functions in the epicardium. Here, we have generated an inducible...

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Detalles Bibliográficos
Autores principales: Ramiro-Pareta, Marina, Müller-Sánchez, Claudia, Portella-Fortuny, Rosa, Soler-Botija, Carolina, Torres-Cano, Alejo, Esteve-Codina, Anna, Bayés-Genís, Antoni, Reina, Manuel, Soriano, Francesc X., Montanez, Eloi, Martínez-Estrada, Ofelia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112914/
https://www.ncbi.nlm.nih.gov/pubmed/36852644
http://dx.doi.org/10.1242/dev.201147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112914/
https://www.ncbi.nlm.nih.gov/pubmed/36852644
http://dx.doi.org/10.1242/dev.201147

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