A new CUT&RUN low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/β-catenin tissue-specific genomic targets

Upon WNT/β-catenin pathway activation, stabilized β-catenin travels to the nucleus where it associates with the TCF/LEF transcription factors, constitutively bound to genomic Wnt-responsive elements (WREs), to activate target gene transcription. Discovering the binding profile of β-catenin is theref...

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Detalles Bibliográficos
Autores principales: Zambanini, Gianluca, Nordin, Anna, Jonasson, Mattias, Pagella, Pierfrancesco, Cantù, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Techniques and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112916/
https://www.ncbi.nlm.nih.gov/pubmed/36355069
http://dx.doi.org/10.1242/dev.201124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112916/
https://www.ncbi.nlm.nih.gov/pubmed/36355069
http://dx.doi.org/10.1242/dev.201124

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