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8-Aminoguanine and Its Actions on Renal Excretory Function

The endogenous purine 8-aminoguanine induces diuresis/natriuresis/glucosuria by inhibiting PNPase (purine nucleoside phosphorylase); however, mechanistic details are unknown. METHODS: Here, we further explored in rats 8-aminoguanine’s effects on renal excretory function by combining studies using in...

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Detalles Bibliográficos
Autores principales: Jackson, Edwin K., Gillespie, Delbert G., Mi, Zaichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112938/
https://www.ncbi.nlm.nih.gov/pubmed/36802842
http://dx.doi.org/10.1161/HYPERTENSIONAHA.122.20760