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Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components

The nuclear architecture of mammalian cells can be altered as a consequence of anomalous accumulation of nuclear proteins or genomic alterations. Most of the knowledge about nuclear dynamics comes from studies on cancerous cells. How normal healthy cells maintain genome stability, avoiding accumulat...

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Detalles Bibliográficos
Autores principales: Muciño-Hernández, Gabriel, Acevo-Rodríguez, Pilar Sarah, Cabrera-Benitez, Sandra, Guerrero, Adán Oswaldo, Merchant-Larios, Horacio, Castro-Obregón, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112964/
https://www.ncbi.nlm.nih.gov/pubmed/36633090
http://dx.doi.org/10.1242/jcs.260563