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Nucleophagy contributes to genome stability through degradation of type II topoisomerases A and B and nucleolar components
The nuclear architecture of mammalian cells can be altered as a consequence of anomalous accumulation of nuclear proteins or genomic alterations. Most of the knowledge about nuclear dynamics comes from studies on cancerous cells. How normal healthy cells maintain genome stability, avoiding accumulat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112964/ https://www.ncbi.nlm.nih.gov/pubmed/36633090 http://dx.doi.org/10.1242/jcs.260563 |