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Characterization of the nuclear import of the human CHD4–NuRD complex

Chromatin remodeling enzymes form large multiprotein complexes that play central roles in regulating access to the genome. Here, we characterize the nuclear import of the human CHD4 protein. We show that CHD4 enters the nucleus by means of several importin-α proteins (1, 5, 6 and 7), but independent...

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Detalles Bibliográficos
Autores principales: Hoffmeister, Helen, Holzinger, Simon, Dürr, Marie-Sofie, Bruckmann, Astrid, Schindler, Susanne, Gröbner-Ferreira, Regina, Depping, Reinhard, Längst, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112965/
https://www.ncbi.nlm.nih.gov/pubmed/36861403
http://dx.doi.org/10.1242/jcs.260724