Disturbed flow increases endothelial inflammation and permeability via a Frizzled-4-β-catenin-dependent pathway

Multidirectional or disturbed flow promotes endothelial dysfunction and is associated with early atherogenesis. Here we investigated the role of Wnt signalling in flow-mediated endothelial dysfunction. The expression of Frizzled-4 was higher in cultured human aortic endothelial cells (ECs) exposed t...

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Detalles Bibliográficos
Autores principales: Rickman, Matthew, Ghim, Mean, Pang, Kuin, von Huelsen Rocha, Ana Cristina, Drudi, Elena M., Sureda-Vives, Macià, Ayoub, Nicolas, Tajadura-Ortega, Virginia, George, Sarah J., Weinberg, Peter D., Warboys, Christina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112981/
https://www.ncbi.nlm.nih.gov/pubmed/36846872
http://dx.doi.org/10.1242/jcs.260449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112981/
https://www.ncbi.nlm.nih.gov/pubmed/36846872
http://dx.doi.org/10.1242/jcs.260449

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