Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models

Neuroinflammation is causally associated with Alzheimer's disease (AD) pathology. Reactive glia cells secrete various neurotoxic factors that impair neuronal homeostasis eventually leading to neuronal loss. Although the glial activation mechanism in AD has been relatively well studied, how it p...

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Detalles Bibliográficos
Autores principales: Sai, Kazuhito, Nakanishi, Aoi, Scofield, Kimberly M., Tokarz, Debra A., Linder, Keith E., Cohen, Todd J., Ninomiya-Tsuji, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112982/
https://www.ncbi.nlm.nih.gov/pubmed/36912451
http://dx.doi.org/10.1242/jcs.260102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10112982/
https://www.ncbi.nlm.nih.gov/pubmed/36912451
http://dx.doi.org/10.1242/jcs.260102

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