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Negative and positive allosteric modulators of the α7 nicotinic acetylcholine receptor regulates the ability of adolescent binge alcohol exposure to enhance adult alcohol consumption

Rationale and Objectives: Ethanol acts directly on the α7 Nicotinic acetylcholine receptor (α7). Adolescent-binge alcohol exposure (ABAE) produces deleterious consequences during adulthood, and data indicate that the α7 receptor regulates these damaging events. Administration of an α7 Negative Allos...

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Detalles Bibliográficos
Autores principales: Rodd, Zachary A., Swartzwelder, H. Scott, Waeiss, R. Aaron, Soloviov, Serhii O., Lahiri, Debomoy K., Engleman, Eric A., Truitt, William A., Bell, Richard L., Hauser, Sheketha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113115/
https://www.ncbi.nlm.nih.gov/pubmed/37082421
http://dx.doi.org/10.3389/fnbeh.2022.954319