Cargando…

Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation

A primary goal in transplantation medicine is the induction of a tolerogenic environment for prevention of transplant rejection without the need for long-term pharmacological immunosuppression. Generation of alloantigen-specific regulatory T cells (Tregs) by transduction with chimeric antigen recept...

Descripción completa

Detalles Bibliográficos
Autores principales: Proics, Emma, David, Marion, Mojibian, Majid, Speck, Madeline, Lounnas-Mourey, Nadia, Govehovitch, Adeline, Baghdadi, Wissam, Desnouveaux, Justine, Bastian, Hervé, Freschi, Laura, Privat, Geoffrey, Pouzet, Cédric, Grossi, Mauro, Heimendinger, Pierre, Abel, Tobias, Fenard, David, Levings, Megan K., Meyer, François, Dumont, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113151/
https://www.ncbi.nlm.nih.gov/pubmed/35931871
http://dx.doi.org/10.1038/s41434-022-00358-x