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Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation
A primary goal in transplantation medicine is the induction of a tolerogenic environment for prevention of transplant rejection without the need for long-term pharmacological immunosuppression. Generation of alloantigen-specific regulatory T cells (Tregs) by transduction with chimeric antigen recept...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113151/ https://www.ncbi.nlm.nih.gov/pubmed/35931871 http://dx.doi.org/10.1038/s41434-022-00358-x |