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Structural basis for enzymatic terminal C–H bond functionalization of alkanes

Alkane monooxygenase (AlkB) is a widely occurring integral membrane metalloenzyme that catalyzes the initial step in the functionalization of recalcitrant alkanes with high terminal selectivity. AlkB enables diverse microorganisms to use alkanes as their sole carbon and energy source. Here we presen...

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Detalles Bibliográficos
Autores principales: Chai, Jin, Guo, Gongrui, McSweeney, Sean M., Shanklin, John, Liu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113152/
https://www.ncbi.nlm.nih.gov/pubmed/36997762
http://dx.doi.org/10.1038/s41594-023-00958-0