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Loss of H3K9 trimethylation alters chromosome compaction and transcription factor retention during mitosis

Recent studies have shown that repressive chromatin machinery, including DNA methyltransferases and polycomb repressor complexes, binds to chromosomes throughout mitosis and their depletion results in increased chromosome size. In the present study, we show that enzymes that catalyze H3K9 methylatio...

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Detalles Bibliográficos
Autores principales: Djeghloul, Dounia, Dimond, Andrew, Cheriyamkunnel, Sherry, Kramer, Holger, Patel, Bhavik, Brown, Karen, Montoya, Alex, Whilding, Chad, Wang, Yi-Fang, Futschik, Matthias E., Veland, Nicolas, Montavon, Thomas, Jenuwein, Thomas, Merkenschlager, Matthias, Fisher, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113154/
https://www.ncbi.nlm.nih.gov/pubmed/36941433
http://dx.doi.org/10.1038/s41594-023-00943-7