Mechanisms of length-dependent recognition of viral double-stranded RNA by RIG-I

Retinoic acid-inducible gene I (RIG-I) is the most front-line cytoplasmic viral RNA sensor and induces antiviral immune responses. RIG-I recognizes short double-stranded (dsRNA) (< 500 bp), but not long dsRNA (> 500 bp) to trigger antiviral signaling. Since RIG-I is capable of binding with dsR...

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Detalles Bibliográficos
Autores principales: Im, Jung Hyun, Duic, Ivana, Yoshimura, Shige H., Onomoto, Koji, Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113236/
https://www.ncbi.nlm.nih.gov/pubmed/37072508
http://dx.doi.org/10.1038/s41598-023-33208-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113236/
https://www.ncbi.nlm.nih.gov/pubmed/37072508
http://dx.doi.org/10.1038/s41598-023-33208-w

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