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Mechanisms of length-dependent recognition of viral double-stranded RNA by RIG-I
Retinoic acid-inducible gene I (RIG-I) is the most front-line cytoplasmic viral RNA sensor and induces antiviral immune responses. RIG-I recognizes short double-stranded (dsRNA) (< 500 bp), but not long dsRNA (> 500 bp) to trigger antiviral signaling. Since RIG-I is capable of binding with dsR...
Autores principales: | Im, Jung Hyun, Duic, Ivana, Yoshimura, Shige H., Onomoto, Koji, Yoneyama, Mitsutoshi, Kato, Hiroki, Fujita, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113236/ https://www.ncbi.nlm.nih.gov/pubmed/37072508 http://dx.doi.org/10.1038/s41598-023-33208-w |
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