Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help

Tissue resident memory (Trm) CD8 T cells infiltrating tumors represent an enriched population of tumor antigen-specific T cells, and their presence is associated with improved outcomes in patients. Using genetically engineered mouse pancreatic tumor models we demonstrate that tumor implantation gene...

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Detalles Bibliográficos
Autores principales: Medler, Terry R., Kramer, Gwen, Bambina, Shelly, Gunderson, Andrew J., Alice, Alejandro, Blair, Tiffany, Zebertavage, Lauren, Duhen, Thomas, Duhen, Rebekka, Young, Kristina, Crittenden, Marka R., Gough, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113239/
https://www.ncbi.nlm.nih.gov/pubmed/37072485
http://dx.doi.org/10.1038/s41598-023-33508-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113239/
https://www.ncbi.nlm.nih.gov/pubmed/37072485
http://dx.doi.org/10.1038/s41598-023-33508-1

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