PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis

Aberrant activation of TGF-β signaling plays a pivotal role in cancer metastasis and progression. However, molecular mechanisms underlying the dysregulation of TGF-β pathway remain to be understood. Here, we found that SMAD7, a direct downstream transcriptional target and also a key antagonist of TG...

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Detalles Bibliográficos
Autores principales: Tian, Han, Liu, Chenying, Yu, Jianchen, Han, Jian, Du, Jianan, Liang, Shujun, Wang, Wenting, Liu, Qin, Lian, Rong, Zhu, Ting, Wu, Shanshan, Tao, Tianyu, Ye, Yaokai, Zhao, Jingjing, Yang, Yi, Zhu, Xun, Cai, Junchao, Wu, Jueheng, Li, Mengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113255/
https://www.ncbi.nlm.nih.gov/pubmed/37072414
http://dx.doi.org/10.1038/s41421-023-00528-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113255/
https://www.ncbi.nlm.nih.gov/pubmed/37072414
http://dx.doi.org/10.1038/s41421-023-00528-0

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