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Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins
Tyrosinase (TYR) and tyrosinase-related proteins 1 and 2 (TYRP1 and TYRP2) are essential for pigmentation. They are generally classified as type-3 copper proteins, with binuclear copper active sites. Although there is experimental evidence for a copper cofactor in TYR, delivered via the copper trans...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113262/ https://www.ncbi.nlm.nih.gov/pubmed/37072620 http://dx.doi.org/10.1038/s42003-023-04640-5 |