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Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins

Tyrosinase (TYR) and tyrosinase-related proteins 1 and 2 (TYRP1 and TYRP2) are essential for pigmentation. They are generally classified as type-3 copper proteins, with binuclear copper active sites. Although there is experimental evidence for a copper cofactor in TYR, delivered via the copper trans...

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Detalles Bibliográficos
Autores principales:	Wagatsuma, Takumi, Suzuki, Eisuke, Shiotsu, Miku, Sogo, Akiko, Nishito, Yukina, Ando, Hideya, Hashimoto, Hisashi, Petris, Michael J., Kinoshita, Masato, Kambe, Taiho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113262/ https://www.ncbi.nlm.nih.gov/pubmed/37072620 http://dx.doi.org/10.1038/s42003-023-04640-5

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