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RIPK3 promoter hypermethylation in hepatocytes protects from bile acid-induced inflammation and necroptosis

Necroptosis facilitates cell death in a controlled manner and is employed by many cell types following injury. It plays a significant role in various liver diseases, albeit the cell-type-specific regulation of necroptosis in the liver and especially hepatocytes, has not yet been conceptualized. We d...

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Detalles Bibliográficos
Autores principales: Hoff, Jessica, Xiong, Ling, Kammann, Tobias, Neugebauer, Sophie, Micheel, Julia M., Gaßler, Nikolaus, Bauer, Michael, Press, Adrian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113265/
https://www.ncbi.nlm.nih.gov/pubmed/37072399
http://dx.doi.org/10.1038/s41419-023-05794-0