Cargando…

Rational peptide design for inhibition of the KIX–MLL interaction

The kinase-inducible domain interacting (KIX) domain is an integral part of the general transcriptional coactivator CREB-binding protein, and has been associated with leukemia, cancer, and various viral diseases. Hence, the KIX domain has attracted considerable attention in drug discovery and develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Nao, Suetaka, Shunji, Hayashi, Yuuki, Arai, Munehito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113271/
https://www.ncbi.nlm.nih.gov/pubmed/37072438
http://dx.doi.org/10.1038/s41598-023-32848-2