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Rational peptide design for inhibition of the KIX–MLL interaction

The kinase-inducible domain interacting (KIX) domain is an integral part of the general transcriptional coactivator CREB-binding protein, and has been associated with leukemia, cancer, and various viral diseases. Hence, the KIX domain has attracted considerable attention in drug discovery and develo...

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Detalles Bibliográficos
Autores principales: Sato, Nao, Suetaka, Shunji, Hayashi, Yuuki, Arai, Munehito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113271/
https://www.ncbi.nlm.nih.gov/pubmed/37072438
http://dx.doi.org/10.1038/s41598-023-32848-2

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