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Rational peptide design for inhibition of the KIX–MLL interaction
The kinase-inducible domain interacting (KIX) domain is an integral part of the general transcriptional coactivator CREB-binding protein, and has been associated with leukemia, cancer, and various viral diseases. Hence, the KIX domain has attracted considerable attention in drug discovery and develo...
Autores principales: | Sato, Nao, Suetaka, Shunji, Hayashi, Yuuki, Arai, Munehito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113271/ https://www.ncbi.nlm.nih.gov/pubmed/37072438 http://dx.doi.org/10.1038/s41598-023-32848-2 |
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