Prion assemblies: structural heterogeneity, mechanisms of formation, and role in species barrier

Prions are proteinaceous pathogens responsible for a wide range of neurodegenerative diseases in animal and human. Prions are formed from misfolded, ß-sheet rich, and aggregated conformers (PrP(Sc)) of the host-encoded prion protein (PrP(C)). Prion replication stems from the capacity of PrP(Sc) to s...

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Detalles Bibliográficos
Autores principales: Igel, Angélique, Fornara, Basile, Rezaei, Human, Béringue, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113350/
https://www.ncbi.nlm.nih.gov/pubmed/36399162
http://dx.doi.org/10.1007/s00441-022-03700-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113350/
https://www.ncbi.nlm.nih.gov/pubmed/36399162
http://dx.doi.org/10.1007/s00441-022-03700-2

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