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Extracellular vesicles with diagnostic and therapeutic potential for prion diseases

Prion diseases (PrD) or transmissible spongiform encephalopathies (TSE) are invariably fatal and pathogenic neurodegenerative disorders caused by the self-propagated misfolding of cellular prion protein (PrP(C)) to the neurotoxic pathogenic form (PrP(TSE)) via a yet undefined but profoundly complex...

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Detalles Bibliográficos
Autores principales: Khadka, Arun, Spiers, Jereme G., Cheng, Lesley, Hill, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113352/
https://www.ncbi.nlm.nih.gov/pubmed/35394216
http://dx.doi.org/10.1007/s00441-022-03621-0