Synthesis, in vitro α-glucosidase inhibitory activities, and molecular dynamic simulations of novel 4-hydroxyquinolinone-hydrazones as potential antidiabetic agents

In the present study, new structural variants of 4-hydroxyquinolinone-hydrazones were designed and synthesized. The structure elucidation of the synthetic derivatives 6a–o was carried out using different spectroscopic techniques including FTIR, (1)H-NMR, (13)C-NMR, and elemental analysis, and their...

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Detalles Bibliográficos
Autores principales: Shayegan, Nahal, Haghipour, Sirous, Tanideh, Nader, Moazzam, Ali, Mojtabavi, Somayeh, Faramarzi, Mohammad Ali, Irajie, Cambyz, Parizad, Sara, Ansari, Shirin, Larijani, Bagher, Hosseini, Samanehsadat, Iraji, Aida, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113378/
https://www.ncbi.nlm.nih.gov/pubmed/37072431
http://dx.doi.org/10.1038/s41598-023-32889-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113378/
https://www.ncbi.nlm.nih.gov/pubmed/37072431
http://dx.doi.org/10.1038/s41598-023-32889-7

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