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Genetic deletion of phosphodiesterase 4D in the liver improves kidney damage in high-fat fed mice: liver-kidney crosstalk

A growing body of epidemiological evidence suggests that nonalcoholic fatty liver disease (NAFLD) is an independent risk factor for chronic kidney disease (CKD), but the regulatory mechanism linking NAFLD and CKD remains unclear. Our previous studies have shown that overexpression of PDE4D in mouse...

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Detalles Bibliográficos
Autores principales: Tao, Xiang, Chen, Can, Huang, Zheng, Lei, Yu, Wang, Muru, Wang, Shuhui, Tian, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113384/
https://www.ncbi.nlm.nih.gov/pubmed/37072403
http://dx.doi.org/10.1038/s41419-023-05792-2