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RIPK1 in the inflammatory response and sepsis: Recent advances, drug discovery and beyond

Cytokine storms are an important mechanism of sepsis. TNF-α is an important cytokine. As a regulator of TNF superfamily receptors, RIPK1 not only serves as the basis of the scaffold structure in complex I to promote the activation of the NF-κB and MAPK pathways but also represents an important prote...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyu, Tang, A-Ling, Chen, Jie, Gao, Nan, Zhang, Guoqiang, Xiao, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113447/
https://www.ncbi.nlm.nih.gov/pubmed/37090690
http://dx.doi.org/10.3389/fimmu.2023.1114103