Cargando…
CD28-signaling can be partially compensated in CD28-knockout mice but is essential for virus elimination in a murine model of multiple sclerosis
The intracerebral infection of mice with Theiler’s murine encephalomyelitis virus (TMEV) represents a well-established animal model for multiple sclerosis (MS). Because CD28 is the main co-stimulatory molecule for the activation of T cells, we wanted to investigate its impact on the course of the vi...
Autores principales: | Hülskötter, Kirsten, Lühder, Fred, Leitzen, Eva, Flügel, Alexander, Baumgärtner, Wolfgang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113529/ https://www.ncbi.nlm.nih.gov/pubmed/37090733 http://dx.doi.org/10.3389/fimmu.2023.1105432 |
Ejemplares similares
-
Ovalbumin-specific CD4(+) and CD8(+) T cells contribute to different susceptibility for Theiler’s murine encephalomyelitis virus persistence
por: Wannemacher, Rouven, et al.
Publicado: (2023) -
Double‐edged effects of tamoxifen‐in‐oil‐gavage on an infectious murine model for multiple sclerosis
por: Hülskötter, Kirsten, et al.
Publicado: (2021) -
Tamoxifen Application Is Associated with Transiently Increased Loss of Hippocampal Neurons following Virus Infection
por: Hülskötter, Kirsten, et al.
Publicado: (2021) -
CD28(−) and CD28(low)CD8(+) Regulatory T Cells: Of Mice and Men
por: Vuddamalay, Yirajen, et al.
Publicado: (2017) -
CD28 Costimulation of T Helper 1 Cells Enhances Cytokine Release In Vivo
por: Langenhorst, Daniela, et al.
Publicado: (2018)