Small-molecule compounds inhibiting S-phase kinase-associated protein 2: A review

S-phase kinase-associated protein 2 (Skp2) is a substrate-specific adaptor in Skp1-CUL1-ROC1-F-box E3 ubiquitin ligases and widely regarded as an oncogene. Therefore, Skp2 has remained as an active anticancer research topic since its discovery. Accordingly, the structure of Skp2 has been solved and...

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Detalles Bibliográficos
Autores principales: Jing, Jia, Rui, Li, Junyuan, Sun, Jinfeng, Yang, Zhihao, Hong, Weiguo, Lu, Zhenyu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113621/
https://www.ncbi.nlm.nih.gov/pubmed/37089937
http://dx.doi.org/10.3389/fphar.2023.1122008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10113621/
https://www.ncbi.nlm.nih.gov/pubmed/37089937
http://dx.doi.org/10.3389/fphar.2023.1122008

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